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After we had seen how relatively easy it was to change the switches in mouse embryos, we thought that perhaps the same could be true of human embryos. In IVF, you also have the embryo for a brief peri
If inheritance was not just about DNA, if these gene switches were so important, just what could turn them on or off? Stephanie and Emend Mullins have two children, Karen and Charlotte. When we were t
It showed that there was clearly more to inheritance than simply the coded sequence of DNA. We then realized that we were dealing with what is now known as genomic imprinting. What genomic imprinting
We are on the brink of uncovering a hidden world, a world that connects past and future generations in ways we never imagined possible. What this means is an environmental exposure that your grandmoth
Our studies had really convinced me that it were the later experiences of the child as the child was growing up bombarded with years and years of, em, symptoms from the parents that accounted for the
The impact of a famine being captured by the genes in the eggs and sperm, and a memory of this event was being carried forward to affect the grandchildren, generations later. We are changing the view